Short Courses

Short Course descriptions are available at the bottom of this page.

Prices are detailed on the registration page.

Morning Short Courses (09h00 - 12h00)

SC-1: Chromatography for dummies – everything you need to know to be able to follow the HPLC conference

PETER SCHOENMAKERS
BOB PIROK

Peter Schoenmakers has been a full-time professor in Analytical Chemistry at the University of Amsterdam since 2002 – with emeritus status since 2021. His has worked on many aspects of one- and two-dimensional chromatography, with a special interest in the characterization of macromolecules. He has seen method-optimization and artificial-intelligence tools emerge some forty years ago, with only gradual progress until recently. Finally, we are starting to see exciting progress in method development for LC.

Together with Bob Pirok, Peter Schoenmakers has recently completed a new textbook on Analytical Separation Science, which is to be launched at HPLC2025 Bruges. He is also the Education Director of COAST, The Netherlands’ public-private-partnership organization on analytical chemistry. From 2005 to 2020 he was an editor of the Journal of Chromatography A. He has received a number of international awards, most recently the ACS Award for Chromatography (2022) and the LCGC lifetime-achievement award (2023).

Bob Pirok obtained his PhD in 2019 in Amsterdam after having worked for several years in industry. He is currently associate professor at the University of Amsterdam where he focuses on the application of chemometrics in analytical chemistry, with a special interest in method development and data analysis for (multi-dimensional) chromatography. He is a visiting research professor at Gustavus Adolphus College in the group of Prof. Dwight Stoll.

He received several international awards, including the Csaba Horváth Young-Scientist Award in 2017, the Journal of Chromatography Award in 2018, and the HTC Innovation Award in 2024 for his work on automation of method development in LC.

He was selected as Early Career Board member for Analytical Chemistry in 2021 and he is Editorial Advisory Board member of the Journal of Separation Science and LC-GC International. He was featured in the 2022 edition of the Power List by The Analytical Scientist.

HPLC for “Dummies”

Bob Pirok and Peter Schoenmakers

van 't Hoff Institute for Molecular Science (HIMS), Faculty of Science, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands, and Centre for Analytical Sciences Amsterdam

We do not expect any real dummies at this course. We do invite participation from scientists with an emerging interest in liquid chromatography (LC) or those for whom it is a minor part of their job. For all of you, HPLC2025 Bruges offers a unique opportunity to learn an awful lot in a single week. However, any of the presentations at the conference may be hard to follow for newcomers. The intention of this very short course is to provide you with sufficient knowledge to make the most out of your participation in the HPLC2025 conference.

In the course we will try to answer the question “What are they talking about?”. For example,

how can we use LC to achieve a separation?
what’s mobile and what’s stationary?
is HPLC high-performance or high-pressure liquid chromatography?
what is the difference between HPLC and ultra-high-pressure liquid chromatography (UHPLC)?
what are core shell particles?
how small is micro-LC? (and how small is nano-LC?)
what is reversed-phase liquid chromatography the opposite of?
why do liquid chromatographers love mass spectrometers?
what is two-dimensional LC and what purposes does it serve?

You should learn the answers to these and many other questions and you will love HPLC2025 Bruges even more after attending this course.

SC-2: Introduction to practical supercritical fluid chromatography

CAROLINE WEST
BENJAMIN CAUX

Caroline West is a full professor in analytical chemistry at the University of Orleans, France, where she is teaching separation science. Her main scientific interests lie in fundamentals of chromatographic selectivity, both in the achiral and chiral modes, in SFC and LC. She is also applying these methods, with or without hyphenation to extraction methods and/or MS, to samples of pharmaceutical interest and natural products. She has authored about 120 papers in international peer‐reviewed journals and has presented about 120 lectures in conferences. In 2015, she received the “LC‐GC Emerging Leader in Chromatography” award. She was ranked several times among the most influential people in analytical chemistry by “The Analytical Scientist” magazine (“Top 40 under 40” 2014 & 2018, “The Power List” 2019, 2020 & 2021), and received the Jubilee medal from the Chromatographic Society (2021). She is also an advisory board member for several journals in separation science (J. Chromatogr. A & Open, J. Sep. Sci., J. Pharm. Biomed. Anal., Chromatographia…)

Benjamin Caux is a PhD student in University of Orléans under the supervision of Caroline West and working for Shimadzu Corporation. He obtained a Bachelor's degree in general chemistry and Master's degree in analytical chemistry at the University of Rouen. His professional background includes experience as an analytical engineer, working on LC, GCxGC, GC-MS and HRMS. His PhD project focuses on innovative method development using supercritical fluid extraction hyphenated with supercritical fluid chromatography and mass spectrometry (SFE-SFC-MS) to analyze plastic additives in medical devices. In this short course, he will bring his technical expertise on using SFC-MS for complex samples.

In this short course, we will introduce you to the basics of analytical supercritical fluid chromatography (SFC) method development. After this course, you will know how to approach any new sample with SFC, starting from sample preparation to final (possibly validated) method, going through choice of detection system, initial screening conditions and optimization steps to achieve a quick, sensitive and robust method. We will also provide comparisons to GC and HPLC, to emphasize the differences and make you understand when SFC should be a good option.

Following the theoretical session, one example will be detailed with a practical "hands-on" session operating a remote instrument.

SC-3: Two-dimensional Liquid Chromatography: Principles, Instrumentation, Method Development, and Applications

DWIGHT STOLL

Dwight Stoll is Professor of Chemistry at Gustavus Adolphus College in St. Peter, MN. He has authored or co-authored more than 100 peer-reviewed publications and five book chapters in separation science, speaks internationally on the topic, and is co-editor of the recent book: Multi-Dimensional Liquid Chromatography: Principles, practice, and applications. He has also written the monthly “LC Troubleshooting” column for LCGC Magazine since 2017, and co-hosts the Analytically Speaking podcast with Prof. Jim Grinias. His primary research focus is on the development of two-dimensional liquid chromatography (2D-LC) for both targeted and untargeted analyses. Within this area he has made contributions on many aspects of the technique including stationary phase characterization, biopharmaceutical analysis, new 2D-LC methodologies and instrumentation, and fundamental aspects including re-equilibration in gradient elution liquid chromatography and analyte focusing. He has taught several short courses on 2D-LC in recent years at venues including Pittcon and the international HPLC20XX series, and hosts multi-day hands-on trainings for multi-dimensional chromatography in his laboratory at Gustavus.

Mel Euerby

Multi-Dimensional Liquid Chromatography: Principles, Practice, and Applications

Description:

Many industries are developing increasingly complex products that require separations with substantially more resolving power than that offered by state-of-the-art one-dimensional liquid chromatography. Two-dimensional liquid chromatography (2D-LC) techniques meet that need and are finding ever more application to the analysis of samples of moderate to high complexity.

This short course will cover:

Concepts of the technique including the theoretical underpinnings of the advantages of 2D separations over their conventional 1D-LC counterparts.
Practical aspects of modern 2D-LC that are critical for the development of successful separations including experimental details, column selection, and the management of the interface between the two separation dimensions.
Applications of 2D-LC described in the literature that address problems in a variety of industries ranging from the analysis of small molecular weight compounds to polymers, which can be chemical as well as biological in nature.
Recent trends towards MD-LC that, by adding further dimensions, allow for deep insights into the structure of biomolecules and have the potential for more automation in analytical workflows.

Instructor:

Dr. Dwight Stoll, Gustavus Adolphus College College, St. Peter, Minnesota, USA.

Dwight is Professor of Chemistry at Gustavus Adolphus College. He has authored or co-authored 100 peer-reviewed publications, six book chapters, and more than 150 conference presentations. He is the co-editor and primary contributor to the recently published book on 2D-LC (ISBN: 978-0-367-54766-0). His primary research focus is on the development of two-dimensional liquid chromatography (2D-LC) for both targeted and untargeted analyses where he made contributions on many aspects of the technique including stationary phase characterization, biopharmaceutical analysis, new 2D-LC methodologies and instrumentation, and fundamentals. Dwight obtained his Ph.D. from the University of Minnesota in 2007, where he worked on the “Development of Fast, Comprehensive Two-Dimensional Liquid Chromatography” in the group of Prof. Dr. Peter Carr. He is the recipient of LCGC’s Emerging Leader in Chromatography Award (2011), the American Chemical Society Division of Analytical Chemistry Award for Young Investigators in Separation Science (2015), the Georges Guiochon Faculty Fellowship (2017), and the Jubilee Medal awarded by the Chromatograpic Society (2021).

SC-4: Microfluidics in separation science: basic principles, microfabrication, analytical and continuous separations of molecules and particles

WIM DE MALSCHE
ILYESSE BIHI

Wim De Malsche is full professor at the Departments of Chemical Engineering Sciences and of Bioengineering Sciences at the Free University of Brussels (VUB), where he teaches on Microfluidics, Microreactors, Microfabrication and Environmental Chemistry. The research of his µFlow group is focused on multi-physics microfluidic approaches aiming for breakthrough technologies in chemical and biotechnological domains. A focus in analytical separations is the recently developed Vortex Chromatography methodology. He is academic director of the open access MICROLAB cleanroom core facility for Si and glass microfabrication. He is coordinator of the Microfluidics spearpoint Research Program SubCellDynamite at VUB (targeting sub-cellular analysis) and of µFlow Cell Group of Excellence in Advanced Research (the microfluidics valorization vehicle at VUB).

Ilyesse Bihi is senior post-doctoral researcher at the Vrije Universiteit Brussel, with a strong academic foundation marked by dual PhDs: one in Chemical Engineering from the University of Florida and another in Micro and Nanotechnologies from Lille University. His research centers on microfluidics, emphasizing innovative approaches to reduce dispersion in chromatography columns through lateral vortices. Additionally, he specializes in microfabrication techniques and the production of drug-loaded microparticles for pharmaceutical applications.

The course will start with a brief overview of microfluidic principles. Typical flow configurations and resulting flow patterns are discussed and relation is made to applications. Next, the most important microfabrication techniques capable to make structures with micron-scale critical dimensions in glass, Si and polymeric material is given. The relation between characteristic dimensions and geometrical channel profiles to chromatographic dispersive behavior is discussed, and solutions to reduce dispersive sources is addressed (pillar array columns, vortex chromatography). Next, configurations that allow to manipulate, direct and separate particles are introduced and discussed (acoustic focusing, di-electrophoresis, deterministic lateral displacement, centrifugal).

Afternoon Short Courses (13h00 - 16h00)

SC-5: The analytical toolbox for the characterization of biopharmaceuticals

DAVY GUILLARME
JONATHAN MAURER

Davy Guillarme, Ph.D. in analytical chemistry from the University of Lyon, France, currently serves as a senior lecturer and research associate at the University of Geneva in Switzerland. With over 350 published journal articles in pharmaceutical analysis and h-index of 77 (Google Scholar), his expertise spans various techniques, including HPLC, UHPLC, HILIC, LC−MS, SFC, SFC-MS, multidimensional LC, and the analysis of biopharmaceuticals.

He is an associate editor of the Journal of Chromatography A. He serves on the editorial advisory board of prestigious journals like Trends in Analytical Chemistry, Journal of Chromatography B, Journal of Separation Science, LC−GC International...

Davy Guillarme has been honored with the LC-GC Emerging Leader Award in Chromatography (2013), the Jubilee Medal from the Chromatographic Society (2018), and the International Award of the Belgian Society of Pharmaceutical Sciences (2022). He has also been listed among the world's most influential analytical scientists by "Analytical Scientist" magazine in multiple years.

Jonathan Maurer is a post-doctoral researcher at the Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, working under Dr. Davy Guillarme. His research focuses on developing advanced chromatographic methods for characterizing mRNA-based drug products in collaboration with Sanofi's mRNA Center of Excellence. He completed his Ph.D. at the University of Lausanne, where he specialized in mass spectrometry quantification of endogenous peptides and their clinical relevance. Jonathan has authored multiple publications in high-impact journals, presented at international conferences, and received over CHF 125,000 in research funding. He is actively involved in scientific communities, including the ccCTA and AFSEP, and contributes as a reviewer for leading journals. Passionate about analytical chemistry and innovation, his work bridges academia and industry to advance pharmaceutical science.

In recent years, there has been a strong evolution of the pharmaceutical landscape, towards more complex, targeted, and personalized therapies, including monoclonal antibodies, and emerging modalities such as oligonucleotides, mRNA, and gene therapies. These innovative molecules are specifically designed to address challenging diseases, like cancer, autoimmune disorders, and rare genetic diseases.

However, to fully benefit from these sophisticated therapies, it is essential to ensure that their quality is consistently high. In this context, advanced analytical techniques are indispensable to ensure batch-to-batch reproducibility, long-term stability under various storage conditions, and the precise detection and quantification of impurities, contaminants and degradation products.

The goal of this short course will be to highlight recent advances to rapidly and accurately characterize these new modalities using diverse chromatographic techniques. Topics will include reversed phase liquid chromatography (RPLC), ion exchange chromatography (IEX), size exclusion chromatography (SEC), hydrophobic interaction chromatography (HIC), hydrophilic interaction chromatography (HILIC), ion pairing reverse phase liquid chromatography (IP-RPLC), or affinity chromatography. Additionally, the short course will explore the integration of chromatographic methods with mass spectrometry (MS) and the application of two-dimensional liquid chromatography (2D-LC) for enhanced analysis.

SC-6: Introduction to Artificial Intelligence for Liquid-phase Separations

BOB PIROK
TIJMEN BOS

Tijmen Bos earned his Ph.D. in 2023 from Vrije Universiteit Amsterdam. Currently, he is a postdoctoral researcher at the University of Amsterdam, specializing in the automated development of methods for chromatographic systems and advanced data analysis. His research is particularly centered on polymer analysis, striving to enhance separation capabilities and develop novel algorithms to extract maximum insights from analytical data. He has a position as a guest researcher in the research group of Professor Dwight Stoll at Gustavus Adolphus College.

It’s no exaggeration to say that artificial intelligence (AI) is transforming science and society. From breakthroughs in molecular discovery to advancements in AI language models, the potential of AI to drive innovation at an unprecedented pace is staggering. Its influence continues to expand, reshaping how we work, learn, and connect with one another. It is therefore not surprising that scientists in analytical separation science also try to capitalize on this potential.

In this course, we will introduce you to artificial intelligence. Like chromatography, artificial intelligence is a vast umbrella representing a large number of techniques. The most important of AI techniques will be discussed.

It is interesting to note that AI has been around for more than half a century. In fact, the technique has undergone two periods of low development, with the Second AI Winter starting around 1984 due to the claims of what AI systems were capable of once more not fulfilling their promise. Indeed, there are also quite some limitations to the successful use of AI, which is why a component of this course will also devote attention to understanding what these limitations are, and that they sometimes cannot be mitigated.

The third component of the course will be a critical overview of less and more successful applications of AI in chromatography and data analysis as well as an attempt to piece together a plausible prediction of what is to come in the upcoming years.

At the conclusion of the course, participants will have the opportunity to see the impact of some of the discussed concepts. A specialized tool will be provided, enabling participants to assess the effects of AI on the optimization process using simulated chromatograms. These chromatograms can either be generated from randomized retention models or derived from user-provided data for personalized testing and analysis. To actively participate in this final interactive part of the course, a (windows) laptop capable of installing third-party software is useful. Performance may vary depending on the device's computational power.

SC-7: Chiral Separations

BEZHAN CHANKVETADZE
WOLFGANG LINDNER

Bezhan Chankvetadze is Professor for Physical Chemistry and director of the Institute of Physical and Analytical Chemistry at the Tbilisi State University in Tbilisi, Georgia.
His research interests include separation sciences with emphases on noncovalent intermolecular interactions, miniaturized techniques, new chiral selectors for liquid-phase separations and enantioselective recognition mechanisms.
He is the Editor-in-Chief of the Journal of Pharmaceutical and Biomedical Analysis and co-editor-in-Chief of the Journal of Pharmaceutical and Biomedical Analysis Open and a member of the editorial boards of Journal of Chromatography A, Journal of Chromatography Open, Electrophoresis, Journal of Separation Science, Journal of Pharmaceutical Analysis, Chirality and several other journals. B. Chankvetadze is the recipient of “Journal of Chromatography Top Cited Article Awards” in 2005, 2006 and 2010, the recipient of “2006 Belgian Society of Pharmaceutical Science Award of Recognition”, the joint Csaba Horvath Memorial Award of the Hungarian Separation Science Society and Connecticut Separation Science Council, USA (2017) and Nernst-Tswett Award from the European Separation Science Society (EuSSS) (2024).

Wolfgang F. Lindner was appointed 1996 the Chair of Analytical Chemistry at the University of Vienna, Austria, and became Emeritus in 2012. His research interests were influenced by pharmaceutical (life) sciences and by separation sciences related to HPLC, SFC, GC, CE/CEC and MS. In this context special interests in his research relates to non-covalent molecular interactions and recognition phenomena within the frame of stereochemistry and enantiomer discrimination.

The development of novel synthetic chiral selectors (receptors) useful for enantioselective separation techniques but also for bioaffinity chromatography lies at the interface of organic, analytical and biological chemistry which characterizes best his scientific credo.
In this context in 1978 he published his first paper on liquid phase enantioseparation, a theme which became a passion throughout his career.
The spectrum of analytical applications spans from bioanalysis, amino acid/peptide analysis, environmental analysis to impurity analysis of bioactive compounds. He has published more than 500 scientific papers, 12 book chapters, holds 15 patents, etc. He has received a number of awards among them are the Chirality Medal, the ACS Award for Chromatography, the AGP Martin Medal, etc.

What will be taught?
1) Short basics of stereochemistry and separation of enantiomers;
2) Comparative characteristics of gas chromatography (GC), high-performance liquid chromatography (HPLC), super/sub-critical fluid chromatography (SFC), capillary electrophoresis (CE) and capillary electrochromatography (CEC) from the viewpoint of chiral separations and enantioselective analysis;
3) Non-covalent interactions and the importance of their control for preparation and use of chiral stationary phases and chiral selectors;
4) Currently available chiral columns and chiral selectors for practical problem solving and their comparative characteristics;
5) Some unusual effects in chiral separations;
6) Understanding enantioselective recognition and chiral separations (kinetics, thermodynamics, molecular modeling).

What we hope to convey to the participants?
1) Understanding of critical differences between achiral and chiral separations;
2) Proper selection of technique for particular problem solving;
3) Proper selection of separation and detection conditions;
4) Understanding of major tools for adjustment and fine tuning of separation process;
5) Adequate interpretation and understanding of separation results;
6) Recent trends in chiral column development and applications.

SC-8: Data treatment processes for large and diverse analytical data sets

RICARDO CUNHA
GERRIT RENNER

Dr Cunha holds a PhD in Environmental Technology from Wageningen University & Research, based in Wetsus in the Netherlands, and an MSc in Biological and Chemical Engineering from the University of Minho in Portugal. Since 1 June 2019, he has been working as a research associate at IUTA in Germany. His work in the Analytical Research and Miniaturisation Department focuses on advanced data analysis, automation, digitalisation, and environmental and analytical technology. He is currently working on projects to develop data processing workflows for predicting equipment maintenance in the laboratory by combining open communication protocols and machine learning techniques. Dr Cunha also investigates chemical and biological transformation processes in wastewater treatment through non-target screening and quality routines for product control using Raman spectroscopy and mass spectrometry. He also has extensive experience in the development of separation and detection methods for the screening of micropollutants in the water cycle.

Links:

www.linkedin.com/in/ricardo-cunha-755308152

https://www.researchgate.net/profile/Jorge-Cunha-8

https://github.com/odea-project/StreamFind

Dr Renner holds a PhD in Analytical Chemistry from the University of Duisburg-Essen and has extensive experience in data processing and algorithm development. He is the lead developer of qAlgorithms, an open-source project that provides a fully automated non-target screening data processing workflow with an extensive quality assurance component and no need for user input parameters. Dr Renner leads the young research group "Analytical Data Science" at the Instrumental Analytical Chemistry group of Prof. Torsten C. Schmidt and has been delivering lectures in chemometrics and applied statistics to master's students for years. He is also an active member of the non-target screening expert committee of the German Chemical Society and a founding member of the PINTS initiative—a community-driven group uniting users and developers of open-source workflows in non-target screening.

Ricardo Cunha^a and Gerrit Renner^b,c

^a Institut für Umwelt & Energie, Technik & Analytik e. V. (IUTA), Bliersheimer Str. 58-60, 47229 Duisburg, Germany

^b Instrumental Analytical Chemistry, University of Duisburg-Essen, Universitätsstr. 5, 45141, Essen, Germany

^c Centre for Water and Environmental Research (ZWU), University of Duisburg-Essen, Universitätsstr. 2, 45141, Essen, Germany

With the increasing complexity of modern analytical techniques and instruments, handling large and diverse datasets has become a crucial skill. This short course gives participants the competencies to flexibly process, inspect, and extract meaningful insights from analytical data.

The session will introduce generic open-source software tools (e.g., StreamFind, KNIME and OpenChrom) and high-level programming languages (i.e., R and Python) and demonstrate how they can efficiently handle analytical data, covering key aspects such as data pre-processing techniques and statistical analysis approaches.

A special focus will be placed on machine learning concepts, particularly the fundamental train-test-predict framework, essential for building reliable predictive models. Participants will gain practical knowledge on applying these techniques effectively in their analytical workflows.

The attendees are encouraged to bring their laptops to maximize their learning experience. This allows hands-on exercises with live demonstration examples – such as quality control of pharmaceuticals using Raman spectroscopy and non-target screening (NTS) based on liquid chromatography and mass spectrometry.

By the end of the short course, participants will have gained competencies in:

The challenges posed by large and complex analytical data sets
Available software tools and techniques for efficient data processing
Statistical methods for extracting valuable patterns and trends
The principles of machine learning and predictive modeling for analytical applications

This interactive session is ideal for professionals, researchers and PhD students looking to enhance their data-handling capabilities and apply advanced analytical techniques in their work.

SC-9: LC-MS and SFC-MS: techniques and data evaluation

GERARD HOPFGARTNER
PATRICK MUELLER

Gérard Hopfgartner received his Ph.D. degree in 1991 at the University of Geneva. Then he moved to Cornell University, USA as a postdoctoral fellow. From 1992 to 2002 he headed the LC-MS group and the bioanalytical section at F. Hoffmann-La Roche in Basel as a scientific expert. In 2002 in joined the School of Pharmaceutical Sciences at the University of Geneva and Lausanne as a Full Professor for analytical sciences and mass spectrometry and since 2015 in the department of Analytical and Inorganic Chemistry. His research interests focus on the development of multimodal mass spectrometry approaches with and without chromatography in the field of life sciences.

Patrick is a German biomolecular engineer and analytical chemist who holds a master´s degree from the Technical University of Darmstadt. During his studies, he conducted research in pharmaceutical and bioanalytical chemistry at the German Cancer Research Center in Heidelberg, the Institute of Molecular Biology in Mainz, and the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland. For his PhD in Life Sciences Mass Spectrometry under the supervision of Prof. Dr. Hopfgartner, Patrick focused on experimental and computational approaches for liquid chromatography (LC) and supercritical fluid chromatography (SFC) in combination with mass spectrometry (MS) for metabolomics and lipidomics. In particular, he developed advanced pipelines for compound identification and custom software tools for the de-novo structural elucidation of lipids based on Electron-Activated Dissociation and Collision-Induced Dissociation of radical cations.

SC-9: LC-MS and SFC-MS: techniques and data evaluation

Patrick Mueller and Gérard Hopfgartner

Life Sciences Mass Spectrometry, University of Geneva, 30 Quai Ernest Ansermet, 1211 Geneva 4, Switzerland

Since its introduction in the early 90’s liquid and supercritical fluid chromatography, using atmospheric pressure ionization, coupled with tandem mass spectrometry (LC-MS, SFC-MS) has become the method of choice in bioanalysis. The goal of this short course is to highlight the benefits and limitations, as well as new developments, of LC-MS and SFC-MS for the analysis of low molecular weight compounds and peptides.

In the first part of the course, the hyphenation of separation sciences with mass spectrometry using electrospray, atmospheric pressure chemical ionization and photoionization is presented. Various current combinations of low- and high-resolution mass instruments and acquisition workflows (e.g. data dependent and date independent acquisition) will be discussed with selected examples.

The second part starts with ion mobility spectrometry, which can be added as an additional separation dimension and various approaches will be presented. Additional MS/MS fragmentation techniques such as ultraviolet photodissociation and electron activated dissociation are described. Quantitative analysis also plays an important role and will be discussed.

The last part of the short course will present data analysis workflows for the general screening of compounds, from feature annotation, feature reduction to library search in large databases.

Full Day Short Courses (09h00 - 12h00 / 13h00 - 16h00))

SC-10: Designing good reversed phase methods: fundamentals and hands-on practicals

MEL EUERBY

Mel Euerby has recently retired as the Principal of Shimadzu’s Centre of Excellence in Liquid Chromatography where he was responsible for inspiring and training young chromatographers for the future. He currently holds Visiting Professor status at the University of Strathclyde and the Open University and has been lecturing for nearly 40 years! Previously, he held the position of Head of R & D and Training at Hichrom Ltd. Prior to that, he worked for 20 years in the pharmaceutical industry where he had global responsibilities for separation science at Astra Zeneca. In 2007 he was awarded the Jubilee Silver Medal for chromatography by The Chromatographic Society. Mel, until recently, was the Educational Officer for The Chromatographic Society with special responsibilities for “chromatographic up-skilling”. Mel’s current areas of interest still include stationary phase characterizations, supercritical fluid

chromatography, analysis of biopharmaceuticals, computerised method development, and fundamental research into retention mechanisms in chromatography.

Mel Euerby

The course will be split into two parts: a theory session in the morning and then a practical “hands-on” session in the afternoon to reinforce the chromatographic principles that have been explained in the morning. The course is aimed at individuals just beginning their chromatographic careers no matter how old they are. The contents will be delivered in an informal and interactive manner. The aims of the course will be to provide the attendees with the relevant chromatographic information to allow them to start to solve chromatographic troubleshooting (not instrumentation), robustness, method development and optimization issues. The course is NOT designed to answer all questions but to set the attendees off in the correct direction to becoming a good chromatographer. The focus of the course will centre on the Resolution Equation and how changing chromatographic operating parameters can have a dramatic effect on the performance of your method. In the afternoon, attendees will have the opportunity to virtually use “state of the art” instrumentation to consolidate what they have learnt in the morning.